🔗 Share this article Patients Discontinuing Anti-Obesity Injections Put On Weight at a Quadrupled Rate Compared to Dieters Weight management often requires ongoing approaches. New research indicates that patients who discontinue blockbuster slimming jabs like Mounjaro or Wegovy may regain reduced body mass far faster than those who halt conventional diet and exercise plans. Findings released in a leading medical journal points out that while obese people frequently drop substantial amounts of their body weight while undergoing treatment, the mass is regained at an estimated rate of nearly a kilo each month after stopping. "Users using these treatments need to be informed of the potential of rapid weight regain when the therapy concludes," warns researcher Dr. Susan Jebb. Such speed of recovery means a reversion to starting mass in about a year and a half. Weighing Approaches The study, which reviewed 37 of studies involving over 9,000 of patients, compared the effects of these new drugs with older methods. Scientists note that people who shed pounds through diet and exercise usually see a slower creep back—approximately 100 grams monthly—once they finish. Understanding the Quick Regain Experts believe the mode of action of the jabs is key to understanding the accelerated weight return. The injections imitate a natural hormone called glucagon-like peptide-1, which helps regulate hunger. "Long-term administration of GLP-1 concentrations far above than the body's typical production might result in the body to generate a reduced amount of its own natural hormone, and may also lessen responsiveness to its effects," noted Dr. Adam Collins, a nutrition specialist. "Stopping of this GLP-1 'fix' means hunger is unsuppressed, making binge eating a significant risk." A Chronic Issue? The NHS suggest the jabs for individuals with weight-linked medical conditions, accompanied by prescribed diet and exercise modifications. Professionals argue that, given the high risk of weight regain, the treatment should be considered ongoing. This view is reinforced by drug manufacturers, who say that the results "underscore the persistent nature of excess weight," comparing it to managing diseases like hypertension. User Accounts Users who have discontinued the jabs report a intense resurgence of hunger. "It was like something activating and I was suddenly starving," said an individual. This challenge is worsened if patients have not established sustainable dietary or behavioural modifications during treatment. Significant Adoption Recent estimates indicate that a significant number of adults in the UK have tried weight-loss jabs in the last 12 months, with interest being substantial. Use is higher among females than men. The middle-aged age group shows the highest usage rates. Many obtain the medications through private prescriptions rather than the NHS. Finally, researchers emphasize that while the jabs are potent agents for shedding pounds, they are not a standalone solution and maintained weight loss relies on combined behavioural support.
Weight management often requires ongoing approaches. New research indicates that patients who discontinue blockbuster slimming jabs like Mounjaro or Wegovy may regain reduced body mass far faster than those who halt conventional diet and exercise plans. Findings released in a leading medical journal points out that while obese people frequently drop substantial amounts of their body weight while undergoing treatment, the mass is regained at an estimated rate of nearly a kilo each month after stopping. "Users using these treatments need to be informed of the potential of rapid weight regain when the therapy concludes," warns researcher Dr. Susan Jebb. Such speed of recovery means a reversion to starting mass in about a year and a half. Weighing Approaches The study, which reviewed 37 of studies involving over 9,000 of patients, compared the effects of these new drugs with older methods. Scientists note that people who shed pounds through diet and exercise usually see a slower creep back—approximately 100 grams monthly—once they finish. Understanding the Quick Regain Experts believe the mode of action of the jabs is key to understanding the accelerated weight return. The injections imitate a natural hormone called glucagon-like peptide-1, which helps regulate hunger. "Long-term administration of GLP-1 concentrations far above than the body's typical production might result in the body to generate a reduced amount of its own natural hormone, and may also lessen responsiveness to its effects," noted Dr. Adam Collins, a nutrition specialist. "Stopping of this GLP-1 'fix' means hunger is unsuppressed, making binge eating a significant risk." A Chronic Issue? The NHS suggest the jabs for individuals with weight-linked medical conditions, accompanied by prescribed diet and exercise modifications. Professionals argue that, given the high risk of weight regain, the treatment should be considered ongoing. This view is reinforced by drug manufacturers, who say that the results "underscore the persistent nature of excess weight," comparing it to managing diseases like hypertension. User Accounts Users who have discontinued the jabs report a intense resurgence of hunger. "It was like something activating and I was suddenly starving," said an individual. This challenge is worsened if patients have not established sustainable dietary or behavioural modifications during treatment. Significant Adoption Recent estimates indicate that a significant number of adults in the UK have tried weight-loss jabs in the last 12 months, with interest being substantial. Use is higher among females than men. The middle-aged age group shows the highest usage rates. Many obtain the medications through private prescriptions rather than the NHS. Finally, researchers emphasize that while the jabs are potent agents for shedding pounds, they are not a standalone solution and maintained weight loss relies on combined behavioural support.